Evolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander Effect
Aman P. Singh, Gail M. Seigel, Leiming Guo, Ashwni Verma, Gloria Gao-Li Wong, Hsuan-Ping Cheng, Dhaval K. Shah
Topics & Concepts
Bystander effectPharmacokineticsIn vivoPharmacodynamicsAntibody-drug conjugatePharmacologyChemistryCancer researchMedicineAntibodyMonoclonal antibodyImmunologyBiologyBiotechnologyHER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchCancer Treatment and Pharmacology