Downregulated ATP6V1B1 expression acidifies the intracellular environment of cancer cells leading to resistance to antibody-dependent cellular cytotoxicity
Mariko Nishie, Eiji Suzuki, Masakazu Hattori, Kosuke Kawaguch, Tatsuki R. Kataoka, Masahiro Hirata, Fengling Pu, Takeshi Kotake, Moe Tsuda, Ayane Yamaguchi, Tomoharu Sugie, Masakazu Toi
Topics & Concepts
GranzymeAntibody-dependent cell-mediated cytotoxicityGranzyme BCytotoxic T cellSKBR3Cancer cellBiologyCell biologyCytotoxicityPerforinChemistryCancerBiochemistryIn vitroHuman breastGeneticsMonoclonal and Polyclonal Antibodies ResearchCell Adhesion Molecules ResearchRNA Interference and Gene Delivery