Targeted treatment of rat AKI induced by rhabdomyolysis using BMSC derived magnetic exosomes and its mechanism
Yuling Chen, Shike Hou
Abstract
: in summary, our proposed method can overcome the shortcomings of poor targeting in traditional exosome therapy. Moreover, in the rhabdomyolysis-induced AKI model, we propose for the first time an exosome therapy mode that directly targets damaged muscles through magnetic navigation.
Topics & Concepts
RhabdomyolysisAcute kidney injuryMicrovesiclesMedicineIncidence (geometry)Mechanism (biology)Internal medicinePharmacologyChemistryBiochemistrymicroRNAGenePhysicsEpistemologyOpticsPhilosophyMuscle and Compartmental DisordersExtracellular vesicles in diseaseCardiovascular Effects of Exercise