Small-molecule control of CAR T cells
Eric L. Adams, Andrew McGovern, Victor So, S. Srinivasan, Alexander Deiters, Jason Lohmueller
Topics & Concepts
Chimeric antigen receptorCytotoxic T cellGenetically engineeredAntigenT cellReceptorCell therapyComputational biologyGenetically modified organismProteaseBiologyImmunologyCell biologyT-cell receptorCellFunction (biology)Fusion proteinCD8Cancer researchChimera (genetics)Genetic enhancementBioinformaticsCAR-T cell therapy researchMonoclonal and Polyclonal Antibodies ResearchProtein Degradation and Inhibitors