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ApoE mimetic peptide targeted nanoparticles carrying a BRD4 inhibitor for treating Medulloblastoma in mice

Qiyue Wang, Virender Kumar, Lin Feng, Bharti Sethi, Donald W. Coulter, Timothy R. McGuire, Ram I. Mahato

2020Journal of Controlled Release38 citationsDOI

Topics & Concepts

ApoptosisApolipoprotein ECancer researchNeurosphereChemistryCell growthVismodegibPharmacologyMolecular biologyBiologyHedgehog signaling pathwayBiochemistryMedicineInternal medicineSignal transductionIn vitroEndothelial stem cellAdult stem cellDiseaseProtein Degradation and InhibitorsChromatin Remodeling and CancerRNA Interference and Gene Delivery
ApoE mimetic peptide targeted nanoparticles carrying a BRD4 inhibitor for treating Medulloblastoma in mice | Litcius