Photocatalytic C–H Thiocyanation of NH<sub>2</sub>-Enaminones and the Tunable Synthetic Routes to 2-Aminothiazoles and 2-Thiazolinones
Junlong Zeng, Jie‐Ping Wan, Yunyun Liu
Abstract
Visible light photocatalytic reactions of NH2-enaminones and ammonium thiocyanate for chemoselective α-C–H thiocyanation have been realized for the first time, providing a sustainable route for the synthesis of thiocyanated NH2-enaminones. In addition, the thiocyanated enaminone products can be flexibly transformed into 2-aminothiazoles and 2-thiazolinones via a simple operation.
Topics & Concepts
Ammonium thiocyanatePhotocatalysisChemistryThiocyanateCombinatorial chemistryReaction conditionsVisible spectrumAmmoniumOrganic chemistryCatalysisMaterials scienceOptoelectronicsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsChemical Synthesis and Reactions