Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia

Chao Wang, Monica Xiong, Maud Gratuze, Xin Bao, Yang Shi, Prabhakar S. Andhey, Melissa Manis, Caitlin M. Schroeder, Zhuoran Yin, Charlotte Madore, Oleg Butovsky, Maxim N. Artyomov, Jason D. Ulrich, David M. Holtzman