Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs
Melissa P. Lokugamage, Daryll Vanover, Jared Beyersdorf, Marine Z. C. Hatit, Laura Rotolo, Elisa Schrader Echeverri, Hannah E. Peck, Huanzhen Ni, Jeong‐Kee Yoon, YongTae Kim, Philip J. Santangelo, James E. Dahlman
Topics & Concepts
ChemistryDrug deliveryMessenger RNAEthylene glycolVirusTherapeutic indexPEG ratioRNAVirologyPharmacologyDrugBiochemistryMedicineGeneEconomicsOrganic chemistryFinanceRNA Interference and Gene DeliverySARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies