TfOH-catalyzed regioselective <i>N</i><sup>2</sup>-alkylation of indazoles with diazo compounds
Hangli He, Jingyu Yan, Jingru Jin, Zhewei Yan, Qiongjiao Yan, Wei Wang, Haipeng Jiang, Haifeng Wang, Fen‐Er Chen
Abstract
up to 100/0) and excellent functional group tolerance. Furthermore, a gram scale synthesis was conducted successfully to give rise to the corresponding products. Mechanistic studies through control experiments provide plausible mechanistic proposals.
Topics & Concepts
AlkylationRegioselectivityDiazoChemistryCatalysisCombinatorial chemistryFunctional groupMetalOrganic chemistryPolymerCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsNanomaterials for catalytic reactions