Novel naphthoquinone-1H-1,2,3-triazole hybrids: Design, synthesis and evaluation as inductors of ROS-mediated apoptosis in the MCF-7 cells
Acácio S. de Souza, Deborah S Dias, Ruan C. B. Ribeiro, Dora C. S. Costa, Matheus G de Moraes, David R Pinho, Maria E G Masset, Laís M Marins, Sandy P. Valle, Cláudio J C de Carvalho, Gustavo Senra Gonçalves de Carvalho, Angélica Lauria do Nascimento Mello, Mauro Sola‐Penna, Marcos V. Palmeira‐Mello, Raissa Alves da Conceição, Carlos Rangel Rodrigues, Alessandra Mendonça Teles de Souza, Luana da Silva Magalhães Forezi, Patrícia Zancan, Vı́tor F. Ferreira, Fernando de Carvalho da Silva
Topics & Concepts
ChemistryApoptosisMCF-7Cancer cellCell cultureProgrammed cell deathCancerCancer researchReactive oxygen speciesPharmacologyBiochemistryBiologyInternal medicineMedicineGeneticsHuman breastBioactive Compounds and Antitumor AgentsSynthesis and biological activityCancer therapeutics and mechanisms