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Numerical simulations of flow patterns in the human left ventricle model with a novel dynamic mesh morphing approach based on radial basis function

Fei Xu, Saša Kenjereš

2021Computers in Biology and Medicine27 citationsDOIOpen Access PDF

Abstract

We present a new numerical simulation framework for prediction of flow patterns in the human left ventricle model. In this study, a radial basis function (RBF) mesh morphing method is developed and applied within the finite-volume computational fluid dynamics (CFD) approach. The numerical simulations are designed to closely mimic details of recent tomographic particle image velocimetry (TomoPIV) experiments. The numerically simulated dynamic motions of the left ventricle and tri-leaflet biological mitral valve are emulated through the RBF morphing method. The arbitrary Lagrangian-Eulerian (ALE) based CFD is performed with the RBF-defined deforming wall boundaries. The results obtained show a good agreement with experiments, confirming the reliability and accuracy of the developed simulation framework.

Topics & Concepts

MorphingParticle image velocimetryRadial basis functionComputational fluid dynamicsComputer scienceSmoothed-particle hydrodynamicsFlow (mathematics)MechanicsPhysicsArtificial intelligenceTurbulenceArtificial neural networkCardiovascular Function and Risk FactorsElasticity and Material ModelingCardiac Valve Diseases and Treatments
Numerical simulations of flow patterns in the human left ventricle model with a novel dynamic mesh morphing approach based on radial basis function | Litcius