High payload and targeted release of anthracyclines by aptamer-tethered DNA nanotrains — Thermodynamic and release kinetic study
Wenxin Pei, Min Liu, Yushu Wu, Yanna Zhao, Tingting Liu, Bin Sun, Yinglin Liu, Qingpeng Wang, Jun Han
Topics & Concepts
Isothermal titration calorimetryChemistryAptamerDrug deliveryBiophysicsHeLaDrug carrierDoxorubicinDaunorubicinBiocompatibilityBiochemistryMolecular biologyIn vitroOrganic chemistryBiologyGeneticsLeukemiaChemotherapyAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryGold and Silver Nanoparticles Synthesis and Applications