A mesoporous polydopamine nanoparticle enables highly efficient manganese encapsulation for enhanced MRI-guided photothermal therapy
Yan Wu, Yu Huang, Chunlai Tu, Fengren Wu, Gangsheng Tong, Yue Su, Xu Li, Xiaoqin Zhang, Shuqiang Xiong, Xinyuan Zhu
Abstract
-weighted MRI effect and photothermal conversion efficiency. Furthermore, MPDAPs/Mn have excellent antitumor efficacy in HeLa tumor-bearing mice. Therefore, this developed MPDAPs/Mn theranostic nanoplatform could be a promising candidate for MRI-guided photothermal cancer therapy.
Topics & Concepts
Photothermal therapyBiocompatibilityMaterials scienceMagnetic resonance imagingNanoparticleNanotechnologyMesoporous materialIn vivoHeLaBiomedical engineeringChemistryIn vitroMedicineRadiologyCatalysisMetallurgyBiotechnologyBiologyBiochemistryNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryExtracellular vesicles in disease