The <i>cwp66</i> Gene Affects Cell Adhesion, Stress Tolerance, and Antibiotic Resistance in Clostridioides difficile
Qingshuai Zhou, Feng-Qin Rao, Zhenghong Chen, Yumei Cheng, Qifang Zhang, Jie Zhang, Zhizhong Guan, Yan He, Wenfeng Yu, Guzhen Cui, Xiaolan Qi, Wei Hong
Abstract
The cell wall protein 66 gene ( cwp66 ) encodes a cell wall protein, which is the second major cell surface antigen of C. difficile . Although immunological approaches, such as antibodies and purified recombinant proteins, have been implemented to study the role of Cwp66 in cell adhesion, no deletion mutant of the cwp66 gene has yet been characterized.
Topics & Concepts
MutantBiologyMicrobiologyGeneMolecular biologyBiochemistryClostridium difficile and Clostridium perfringens researchBacterial Identification and Susceptibility TestingAntimicrobial Resistance in Staphylococcus