Disrupted Excitatory Synaptic Contacts and Altered Neuronal Network Activity Underpins the Neurological Phenotype in PCDH19-Clustering Epilepsy (PCDH19-CE)
Stefka Mincheva-Tasheva, Alvaro F. Nieto Guil, Claire C. Homan, Jozef Gécz, Paul Q. Thomas
Topics & Concepts
BiologySynaptogenesisNeurosciencePhenotypeNeuriteEpilepsyExcitatory postsynaptic potentialNeurogenesisMissense mutationGeneGeneticsInhibitory postsynaptic potentialIn vitroNeuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental DisordersRNA regulation and disease