Should mutant TP53 be targeted for cancer therapy?
Zilu Wang, Andreas Strasser, Gemma L. Kelly
Topics & Concepts
MutantCarcinogenesisDNA damageBiologyCancer researchCancer cellCancerSuppressorDNA repairGeneMutationCell growthCell cycleCell cycle checkpointTranscription factorMalignant transformationSenescenceCell biologyDNAGeneticsCancer-related Molecular PathwaysUbiquitin and proteasome pathwaysCancer, Hypoxia, and Metabolism