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CTLA-4 tail fusion enhances CAR-T antitumor immunity

Xiaoyu Zhou, Hanbing Cao, Shao‐Yu Fang, Ryan D. Chow, Kaiyuan Tang, Medha Majety, Meizhu Bai, Matthew B. Dong, Paul Renauer, Xingbo Shang, Kazushi Suzuki, Andre Levchenko, Sidi Chen

2023Nature Immunology50 citationsDOIOpen Access PDF

Topics & Concepts

Chimeric antigen receptorCytotoxic T cellT cellAntigenCell biologyBiologyImmune systemCancer researchImmunologyChemistryIn vitroGeneticsCAR-T cell therapy researchNanowire Synthesis and ApplicationsVirus-based gene therapy research
CTLA-4 tail fusion enhances CAR-T antitumor immunity | Litcius