Constrained maximum likelihood-based Mendelian randomization robust to both correlated and uncorrelated pleiotropic effects
Haoran Xue, Xiaotong Shen, Wei Pan
Topics & Concepts
Mendelian randomizationPleiotropyGenome-wide association studyConfoundingInstrumental variableComputer scienceEconometricsSingle-nucleotide polymorphismStatisticsBiologyGeneticsMathematicsGenetic variantsGeneGenotypePhenotypeGenetic Associations and EpidemiologyGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals