Gamma-oryzanol alleviates intervertebral disc degeneration development by intercepting the IL-1β/NLRP3 inflammasome positive cycle
Hui Xu, Zi-Han Dai, Gao-Lu He, Hanchen Cai, Xuanyang Chen, Yanlin Chen, Cong Xu, Sunren Sheng
Topics & Concepts
InflammasomeIn vivoMatrix metalloproteinaseMedicineDegeneration (medical)Intervertebral discInflammationChemistryCell biologyPharmacologyPathologyBiochemistryBiologyInternal medicineBiotechnologyAnatomySpine and Intervertebral Disc PathologyPain Mechanisms and TreatmentsSesquiterpenes and Asteraceae Studies