From Effective Interactions Extracted Using Hi-C Data to Chromosome Structures in Conventional and Inverted Nuclei
Sucheol Shin, Guang Shi, D. Thirumalai
Abstract
The authors of this paper extract interaction energies from Hi-C data and use the inferred parameters to develop a polymer model that replicates segregation and other features observed in chromatin structures.
Topics & Concepts
ChromatinChromosomeComputer scienceBiological systemBiologyPhysicsGeneticsDNAGeneGenomics and Chromatin DynamicsRNA and protein synthesis mechanismsRNA Research and Splicing