Use of tafenoquine to treat a patient with relapsing babesiosis with clinical and molecular evidence of resistance to azithromycin and atovaquone
Luis A. Marcos, Annie Leung, Laura A. Kirkman, Gary P. Wormser
Abstract
Tafenoquine is a highly effective treatment for Babesia microti infections in animal models. An immunocompromised patient infected by a strain of B. microti that was at least partially resistant to both azithromycin and atovaquone was treated with tafenoquine. Systematic clinical studies using tafenoquine for treating other patients with babesiosis should be considered.
Topics & Concepts
AtovaquoneAzithromycinMedicineBabesiosisVirologyImmunologyMalariaMicrobiologyBiologyPlasmodium falciparumAntibioticsVector-borne infectious diseasesInsect and Pesticide ResearchMosquito-borne diseases and control