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Super-resolution microscopy: Shedding new light on blood cell imaging

Huan Deng, Yan Ma, Yuhui Zhang

2024Journal of Innovative Optical Health Sciences6 citationsDOIOpen Access PDF

Abstract

Blood cells are the most integral part of the body, which are made up of erythrocytes, platelets and white blood cells. The examination of subcellular structures and proteins within blood cells at the nanoscale can provide valuable insights into the health status of an individual, accurate diagnosis, and efficient treatment strategies for diseases. Super-resolution microscopy (SRM) has recently emerged as a cutting-edge tool for the study of blood cells, providing numerous advantages over traditional methods for examining subcellular structures and proteins. In this paper, we focus on outlining the fundamental principles of various SRM techniques and their applications in both normal and diseased states of blood cells. Furthermore, future prospects of SRM techniques in the analysis of blood cells are also discussed.

Topics & Concepts

MicroscopyLight sheet fluorescence microscopyResolution (logic)Super-resolution microscopyOpticsMaterials scienceScanning confocal electron microscopyPhysicsComputer scienceArtificial intelligenceCell Image Analysis TechniquesDigital Holography and MicroscopySpectroscopy Techniques in Biomedical and Chemical Research
Super-resolution microscopy: Shedding new light on blood cell imaging | Litcius