Catalytic and Multicomponent Reactions for Green Synthesis of Some Pyrazolone Compounds and Evaluation as Antimicrobial Agents
Hazim M. Ali, Yasser A. El-Ossaily, Saoud A. Metwally, Ibrahim O. Althobaiti, Hamud A. Altaleb, Yousra A. Naffea, Mahmoud S. Tolba
Abstract
). The chemical structure of the novel designed derivatives was ascertained based on elemental analyses, mp, thin-layer chromatography, and spectral analyses. Furthermore, some of the synthesized derivatives were examined against different pathogenic bacterial and fungal strains. Their results demonstrated that some of them revealed notable antimicrobial activities.
Topics & Concepts
ChemistryPyrazoloneCatalysisPyrazolineImidazoleHydrogen peroxideAntimicrobialAqueous solutionDerivative (finance)Organic chemistryPyrazolonesElectrophileCombinatorial chemistryEconomicsFinancial economicsChemistry and Chemical EngineeringMulticomponent Synthesis of HeterocyclesSynthesis and biological activity