Novel urea linked ciprofloxacin-chalcone hybrids having antiproliferative topoisomerases I/II inhibitory activities and caspases-mediated apoptosis
Hamada H.H. Mohammed, Samar H. Abbas, Alaa M. Hayallah, Gamal El‐Din A. Abuo‐Rahma, Yaser A. Mostafa
Topics & Concepts
ChemistryCamptothecinApoptosisChalconeCaspaseTopotecanCytotoxic T cellCytochrome cCancer cellStaurosporineMolecular biologyCancer researchBiochemistryProgrammed cell deathStereochemistryIn vitroCancerBiologyKinaseGeneticsChemotherapyProtein kinase CCancer therapeutics and mechanismsLung Cancer Research StudiesBioactive Compounds and Antitumor Agents