A Paradoxical AKT: Exploring the Promise and Challenges of PI3K/AKT/mTOR Targeted Therapies
Gennie L. Parkman, Sheri L. Holmen
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BmTORC2Discovery and development of mTOR inhibitorsMedicineBiologymTORC1Signal transductionCell biologyProtein Degradation and InhibitorsPI3K/AKT/mTOR signaling in cancer