Structural optimization, synthesis and in vitro synergistic anticancer activities of combinations of new N3-substituted dihydropyrimidine calcium channel blockers with cisplatin and etoposide
Marwa H. El‐Wakil, Mohamed Teleb, Marwa M. Abu‐Serie, Sun Huang, Gerald W. Zamponi, Hesham Fahmy
Topics & Concepts
ChemistryEtoposideCisplatinCalcium channelStereochemistryPharmacologyCancer cellIn vitroIn silicoChannel blockerCalciumCancerBiochemistryChemotherapyOrganic chemistryMedicineGeneSurgeryInternal medicineSynthesis and Biological EvaluationCancer therapeutics and mechanismsSynthesis and biological activity