Safety and Efficacy of Amiodarone in a Patient With COVID-19
Nadia Castaldo, Alberto Aimo, Vincenzo Castiglione, C. Padalino, Michele Emdin, Carlo Tascini
Abstract
There is an urgent need for effective treatments for coronavirus disease-2019 (COVID-19). Amiodarone, like hydroxychloroquine, exerts antiviral actions by interfering with endocytosis and viral replication. Here, to our knowledge, we report the first case of a patient affected by respiratory failure related to COVID-19 who recovered after only supportive measures and a short amiodarone course. (Level of Difficulty: Beginner.)
Topics & Concepts
AmiodaroneCoronavirus disease 2019 (COVID-19)HydroxychloroquineMedicine2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CoronavirusVirologyIntensive care medicinePharmacologyInternal medicineDiseaseAtrial fibrillationInfectious disease (medical specialty)OutbreakCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Researchinterferon and immune responses