Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo
Pierre‐Jean Le Reste, Raphaël Pineau, Konstantinos Voutetakis, Juhi Samal, Gwénaële Jégou, Stéphanie Lhomond, Adrienne M. Gorman, Afshin Samali, John B. Patterson, Qingping Zeng, Abhay Pandit, Marc Aubry, Nicolas Soriano, Amandine Etcheverry, Aristotelis Chatziioannou, Jean Mosser, Tony Avril, Éric Chevet
Topics & Concepts
MedicineChemotherapyGlioblastomaIn vivoRegimenCancer researchDiseaseEndoplasmic reticulumOncologyUnfolded protein responsePathologyInternal medicineBiologyBiotechnologyBiochemistryEndoplasmic Reticulum Stress and DiseaseMitochondrial Function and PathologyGlioma Diagnosis and Treatment