FOXO3a-dependent up-regulation of HSP90 alleviates cisplatin-induced apoptosis by activating FUNDC1-mediated mitophagy in hypoxic osteosarcoma cells
Dian Lu, Rui Liu, Yuting Zhou, Zhenbo Zhang, Xiuqin Jiang, Jinjin Xu, Airong Su, Zhenzhen Hu
Topics & Concepts
MitophagySmall interfering RNATransfectionAutophagyCancer researchCell biologyApoptosisCisplatinHypoxia (environmental)ChemistryMolecular biologyBiologyBiochemistryOxygenOrganic chemistryChemotherapyGeneticsGeneAutophagy in Disease and TherapyFOXO transcription factor regulationMicroRNA in disease regulation