Discovery of novel BCL6-Targeting PROTACs with effective antitumor activities against DLBCL in vitro and in vivo
Dazhao Mi, Li Cheng, Yuzhan Li, Mingyue Yao, Yan Li, Keyu Hong, Chengying Xie, Yihua Chen
Topics & Concepts
BCL6LymphomaChemistryCancer researchIn vivoIn vitroCarcinogenesisB cellImmunologyBiologyBiochemistryGeneticsGeneGerminal centerAntibodyProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments