Effectiveness of Self-assembling Peptide P11-4 Compared to Tricalcium Phosphate Fluoride Varnish in Remineralization of White Spot Lesions: A Clinical Randomized Trial
Essam Osman, Riham Kobeissi, Sherine Badr
Abstract
BACKGROUND: -4 (Curodont Repair, CDR) works on a different scale in treating WSLs by mimicking the enamel matrix and aiming to guided enamel regeneration. AIM: -4 vs tricalcium posphate fluoride (TCPF) in remineralization of WSLs in young permanent teeth. MATERIALS AND METHODS: -4 (group II). Lesions were assessed at pretreatment, 3, and 6 months posttreatment quantitatively per laser fluorescence DIAGNOdent pen and qualitatively through the International Caries Detection and Assessment System (ICDAS) II. RESULTS: -4 compared to TCPF varnish. CONCLUSION: -4 through the biomineralization has proven superiority of this material compared to TCPF. CLINICAL SIGNIFICANCE: Early detection of WSLs and minimal intervention through remineralizing agents can limit unnecessary tissue loss, further caries progression, and consequently prevent further harm to the patients. HOW TO CITE THIS ARTICLE: -4 Compared to Tricalcium Phosphate Fluoride Varnish in remineralization of White Spot Lesions: A Clinical Randomized Trial. Int J Clin Pediatr Dent 2020;13(5):451-456.