TGF-β promote epithelial-mesenchymal transition via NF‐κB/NOX4/ROS signal pathway in lung cancer cells
Mingze Ma, Fengxian Shi, Ruonan Zhai, Hang Wang, Ke Li, Chunyan Xu, Wu Yao, Fang Zhou
Topics & Concepts
Epithelial–mesenchymal transitionNOX4A549 cellChemistryTransforming growth factorMolecular biologyCancer researchNF-κBVimentinCancer cellCell growthBiologyCell biologySignal transductionNADPH oxidaseReactive oxygen speciesCellDownregulation and upregulationCancerBiochemistryImmunologyImmunohistochemistryGeneGeneticsCancer Cells and MetastasisCancer-related molecular mechanisms researchTGF-β signaling in diseases