Maintaining blood retinal barrier homeostasis to attenuate retinal ischemia-reperfusion injury by targeting the KEAP1/NRF2/ARE pathway with lycopene
Hao Huang, Xielan Kuang, Xiaobo Zhu, Hao Cheng, Yuxiu Zou, Han Du, Han Tang, Linbin Zhou, Jingshu Zeng, Huijun Liu, Jianhua Yan, Chongde Long, Huangxuan Shen
Topics & Concepts
RetinalRetinal pigment epitheliumRetinaCell biologyReperfusion injuryBlood–retinal barrierIschemiaBiologyPharmacologyChemistryBiochemistryMedicineInternal medicineEndocrinologyNeuroscienceDiabetic retinopathyDiabetes mellitusAntioxidant Activity and Oxidative StressCardiovascular, Neuropeptides, and Oxidative Stress ResearchGenomics, phytochemicals, and oxidative stress