Litcius/Paper detail

Ulcerative colitis alleviation of colon-specific delivered rhamnolipid/fullerene nanocomposites <i>via</i> dual modulation in oxidative stress and intestinal microbiome

Yuxuan Xia, Liu Hong, Jiayao Zheng, Ziyi Lu, Qiong Zhang, Siyu Chen, Zhi Pang, Lei Li, Shumiao Qiao, Qiang Wang, Yonghua Zhou, Cheng Yang

2023Journal of Materials Chemistry B12 citationsDOI

Abstract

Ulcerative colitis inflammation is profoundly alleviated by colon-targeting delivery of low dose (0.4 mg kg −1 ) rhamnolipid/fullerene nanocomposites via the synergism of oxidative stress mitigation and gut microbiome recovery.

Topics & Concepts

Oxidative stressUlcerative colitisMicrobiomeRhamnolipidMaterials scienceIntestinal MicrobiomeDual (grammatical number)FullereneModulation (music)ColitisMicrobiologyImmunologyMedicineBacteriaChemistryInternal medicineBiologyBioinformaticsPseudomonas aeruginosaOrganic chemistryPhysicsAcousticsGeneticsDiseaseLiteratureArtNanoparticle-Based Drug DeliveryGraphene and Nanomaterials ApplicationsNanoparticles: synthesis and applications