Nanoparticle-Loaded Hydrogel for the Light-Activated Release and Photothermal Enhancement of Antimicrobial Peptides
Samuel C. T. Moorcroft, Lucien Roach, David Jayne, Zhan Yuin Ong, Stephen D. Evans
Abstract
, indicating that the therapeutic gel has the potential for multiple rounds of treatment. Taken together, this novel therapeutic hydrogel system demonstrates the stimuli-responsive release of AMPs with photothermal enhanced antimicrobial efficacy to treat pathogenic bacteria.
Topics & Concepts
Photothermal therapyAntimicrobialPhotothermal effectMaterials scienceAntimicrobial peptidesEthylene glycolStaphylococcus aureusSelf-healing hydrogelsBiophysicsDrug deliveryBacteriaNanotechnologyMicrobiologyChemistryBiologyOrganic chemistryPolymer chemistryGeneticsAntimicrobial Peptides and ActivitiesNanoplatforms for cancer theranosticsPolydiacetylene-based materials and applications