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β-glucan, a specific immuno-stimulant, produces rapid antidepressant effects by stimulating ERK1/2-dependent synthesis of BDNF in the hippocampus

Bingran Chen, Cheng Zhao, Hao‐Jie Zhu, Xu Lu, Huijun Liu, Qun Lu, Tao Zhu, Chao Huang

2023European Journal of Pharmacology24 citationsDOI

Topics & Concepts

Dentate gyrusNeurotrophic factorsAntidepressantMicrogliaBrain-derived neurotrophic factorPharmacologyHippocampusEndocrinologyGlucanInternal medicineChemistryMedicineReceptorInflammationBiochemistryTryptophan and brain disordersStress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms
β-glucan, a specific immuno-stimulant, produces rapid antidepressant effects by stimulating ERK1/2-dependent synthesis of BDNF in the hippocampus | Litcius