A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Ran Liu, Lei He, Yuansheng Hu, Zhaofeng Luo, Jingjing Zhang
Abstract
selection can obtain aptamers selective for many COVID-19-associated antigens, the method demonstrated here will serve as an important tool for the diagnosis and therapeutics of COVID-19.
Topics & Concepts
AptamerCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Virology2019-20 coronavirus outbreakSerologyLigationMedicineBiologyImmunologyMolecular biologyAntibodyInfectious disease (medical specialty)PathologyOutbreakDiseaseAdvanced biosensing and bioanalysis techniquesSARS-CoV-2 detection and testingRNA Interference and Gene Delivery