Mitochondria-targeted delivery and light controlled release of iron prodrug and CO to enhance cancer therapy by ferroptosis
Fan Gao, Fei Wang, Xuan Nie, Ze Zhang, Guang Chen, L. Xia, Long‐Hai Wang, Changhui Wang, Zong-Yao Hao, Wenjian Zhang, Chun‐Yan Hong, Ye‐Zi You
Abstract
Mitochondrial malfunction is considered to be a decisive signal of apoptosis.
Topics & Concepts
ChemistryProdrugMitochondrionCancer therapyCancerCancer researchPharmacologyBiochemistryInternal medicineMedicineBiologyHeme Oxygenase-1 and Carbon MonoxideFerroptosis and cancer prognosisNanoplatforms for cancer theranostics