CAR-T cells targeting a nucleophosmin neoepitope exhibit potent specific activity in mouse models of acute myeloid leukaemia
Guozhu Xie, Nikola A. Ivica, Bin Jia, Yingzhong Li, Han Dong, Yong Liang, Douglas Brown, Rizwan Romee, Jianzhu Chen
Topics & Concepts
AntigenCancer researchMyeloidBiologyHuman leukocyte antigenEpitopeCytotoxic T cellImmunologyIn vitroGeneticsCAR-T cell therapy researchVirus-based gene therapy researchImmunotherapy and Immune Responses