Synthesis of 1,3‐Diynes Using Calcium Carbide as an Alkyne Source
Zhenrong Liu, Zheng Li
Abstract
Abstract A simple method for the synthesis of 1,3‐diynes from iodoarenes using calcium carbide as an alkyne source and air as an oxidant is described. A series of 1,4‐diarylbuta‐1,3‐diynes were efficiently synthesized by this strategy. The salient features of this protocol are the use of inexpensive and easy‐to‐handle alkyne source, broad substrate scope, open‐air condition, and simple operation procedure.
Topics & Concepts
AlkyneChemistryCalcium carbideCombinatorial chemistryScope (computer science)Substrate (aquarium)CarbideOrganic chemistryCatalysisComputer scienceOceanographyProgramming languageGeologyCatalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsSynthesis and Characterization of Pyrroles