Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome
Zhikuan Zhang, Takuma Shibata, Akiko Fujimura, Jiro Kitaura, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu
Topics & Concepts
InflammasomeNLRP1Innate immune systemCell biologyAllosteric regulationChemistryPyrin domainThioredoxinBiologyBiochemistryApoptosisReceptorGeneCaspaseProgrammed cell deathInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideEndoplasmic Reticulum Stress and Disease