Lobetyolin, a Q-marker isolated from Radix Platycodi, exerts protective effects on cisplatin-induced cytotoxicity in HEK293 cells
Yun‐yi Hou, Si-min Qi, Jing Leng, Qiong Shen, Shan Tang, Jing-Tian Zhang, Junnan Hu, Shuang Jiang, Wei Li
Topics & Concepts
CytotoxicityHEK 293 cellsApoptosisCisplatinMAPK/ERK pathwayPhosphorylationp38 mitogen-activated protein kinasesReactive oxygen speciesTumor necrosis factor alphaViability assayChemistryBlotMolecular biologyCell biologyBiologyReceptorBiochemistryIn vitroImmunologyGeneticsChemotherapyGeneChemotherapy-induced organ toxicity mitigationAcute Lymphoblastic Leukemia researchArsenic contamination and mitigation