LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

Lawrence P. Andrews, Samuel C. Butler, Jian Cui, Anthony R. Cillo, Carly Cardello, Chang Liu, Erin A. Brunazzi, Andrew Baessler, Bingxian Xie, Sheryl Kunning, Shin Foong Ngiow, Yinghui Huang, Sasikanth Manne, Arlene H. Sharpe, Greg M. Delgoffe, E. John Wherry, John M. Kirkwood, Tullia C. Bruno, Creg J. Workman, Dario A.A. Vignali