Carnitine promotes recovery from oxidative stress and extends lifespan in C. elegans
Dongliang Liu, Xiaofang Zeng, Le Li, Zhenglin Ou
Abstract
mutants and its knockdown prevents L-carnitine from improving oxidative stress recovery and prolonging lifespan. Together, our study suggests an important role of L-carnitine in oxidative stress recovery that might be important for healthy aging in humans.
Topics & Concepts
Oxidative stressCaenorhabditis elegansCell biologyBiologyCarnitineOxidative phosphorylationChemistryGeneticsEndocrinologyBiochemistryGeneMitochondrial Function and PathologyMetabolism and Genetic DisordersDiet and metabolism studies