LC3A-mediated autophagy regulates lung cancer cell plasticity
Chia‐Cheng Miao, Wen Hwang, Ling-Yi Chu, Lihao Yang, Cam-Thu Ha, Pei‐Yu Chen, Ming-Han Kuo, Sheng‐Chieh Lin, Yayu Yang, Shuang‐En Chuang, Chia-Cherng Yu, Shien‐Tung Pan, Mou‐Chieh Kao, Chuang‐Rung Chang, Yu‐Ting Chou
Abstract
ABBREVIATIONS: : short hairpin RNA; SNAI2: snail family transcriptional repressor 2; SOX2: SRY-box transcription factor 2; SQSTM1/p62: sequestosome 1; TGFB/TGF-β: transforming growth factor beta; TOMM20: translocase of outer mitochondrial membrane 20; ZEB1: zinc finger E-box binding homeobox 1.
Topics & Concepts
BiologySequestosome 1Molecular biologyCell biologyAutophagyBiochemistryApoptosisRNA modifications and cancerAutophagy in Disease and TherapyMicroRNA in disease regulation