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Linezolid-induced black hairy tongue in a patient with multidrug-resistant tuberculosis: A case report

Jaemin Lee, Hyun Sung Chung, Jiyeon Roh, Yeseul Oh, Jeongha Mok

2021Science Progress18 citationsDOIOpen Access PDF

Abstract

The revised World Health Organization guidelines on multidrug-resistant tuberculosis include linezolid in the core drugs group. Consequently, the use of linezolid for patients with multidrug-resistant tuberculosis is increasing. Common adverse events of long-term linezolid use include bone marrow suppression and neuropathies. However, there is limited information on a rare adverse event, black hairy tongue. Here, we report a case of linezolid-induced black hairy tongue in a patient with multidrug-resistant tuberculosis. The etiology, pathogenesis, diagnosis, and treatment of black hairy tongue are also discussed.

Topics & Concepts

LinezolidMedicineTuberculosisAdverse effectTongueEtiologyMultiple drug resistanceDermatologyIntensive care medicineInternal medicinePathologyAntibioticsMicrobiologyBiologyGeneticsBacteriaVancomycinStaphylococcus aureusOral Health Pathology and TreatmentMycobacterium research and diagnosisAutoimmune and Inflammatory Disorders