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Dystrophin Gene-Editing Stability Is Dependent on Dystrophin Levels in Skeletal but Not Cardiac Muscles

Niclas E. Bengtsson, Hichem Tasfaout, Stephen D. Hauschka, Jeffrey S. Chamberlain

2020Molecular Therapy25 citationsDOIOpen Access PDF

Topics & Concepts

DystrophinDuchenne muscular dystrophySkeletal muscleBiologyGenome editingMuscular dystrophyExonExon skippingGuide RNARegeneration (biology)mdx mouseCell biologyCRISPRGeneticsMolecular biologyGeneAlternative splicingEndocrinologyCRISPR and Genetic EngineeringVirus-based gene therapy researchMuscle Physiology and Disorders
Dystrophin Gene-Editing Stability Is Dependent on Dystrophin Levels in Skeletal but Not Cardiac Muscles | Litcius