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Electrochemically-promoted synthesis of benzo[<i>b</i>]thiophene-1,1-dioxides <i>via</i> strained quaternary spirocyclization

Rui-Tao Li, Da-Fu Yuan, Mengqi Ping, Yu-Yi Zhu, Shao‐Fei Ni, Ming Li, Li‐Rong Wen, Lin‐Bao Zhang

2022Chemical Science30 citationsDOIOpen Access PDF

Abstract

-attack, the S-migration process was rationalized to lead to the products. Computational studies revealed the selectivity and the compatibility of drug molecules showcased the potential application of the protocols.

Topics & Concepts

BenzothiopheneThiopheneChemistryElectrochemistryCombinatorial chemistrySelectivityMoleculeCatalysisOrganic chemistryPhysical chemistryElectrodeSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods
Electrochemically-promoted synthesis of benzo[<i>b</i>]thiophene-1,1-dioxides <i>via</i> strained quaternary spirocyclization | Litcius