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Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models

Ekram Ahmed Chowdhury, Guy Meno‐Tetang, Hsueh Yuan Chang, Shengjia Wu, Hsien Wei Huang, Tanguy Jamier, Jayanth Chandran, Dhaval K. Shah

2021Advanced Drug Delivery Reviews75 citationsDOI

Topics & Concepts

MedicinePharmacokineticsPharmacologyComputational biologyDosingPharmacodynamicsImmunogenicityBiologyImmune systemImmunologyVirus-based gene therapy researchRNA Interference and Gene DeliveryAnimal Virus Infections Studies
Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models | Litcius