In silico screening of chalcone derivatives as promising EGFR-TK inhibitors for the clinical treatment of cancer
Shalini Mathpal, Tushar Joshi, Priyanka Sharma, Priyanka Maiti, Mahesha Nand, Veena Pande, Subhash Chandra
Topics & Concepts
Lipinski's rule of fiveErlotinibVirtual screeningChalconeEGFR inhibitorsEpidermal growth factor receptorWnt signaling pathwayDocking (animal)In silicoChemistryComputational biologyChemical spaceBiochemistryCancer researchDrug discoveryBiologyStereochemistrySignal transductionReceptorMedicineNursingGeneHER2/EGFR in Cancer ResearchComputational Drug Discovery MethodsLung Cancer Treatments and Mutations